Hurthle cell cancer

This tumor originates from the oncocytes of the thyroid gland

Hürthle cell cancer is a tumor of the thyroid gland. It can be benign or, to a lesser extent, malignant when it invades neighboring tissues or spreads to other organs.

This tumor originates from the oncocytes of the thyroid gland.

Hürthle cell cancer is usually asymptomatic but may present with visible growth of the thyroid.

Its treatment is surgical extraction, so suspicion is required.

Hürthle cell cancer is a cytological variant of follicular thyroid carcinoma, but more aggressive.

It is considered the most aggressive because there is greater lymphatic involvement that leads to lymph node dissemination or metastasis, in addition to hematic dissemination.

On the other hand, they usually have a poor response to radioactive iodine therapy.

Askanazy cell tumor accounts for 3-4% of all thyroid cancers and 25% of follicular carcinomas.

In the literature, it is considered an intermediate grade tumor, since between 20 and 33% of Hürthle cell cancers have malignant behavior evidenced by their invasive growth and the ability to metastasize at a distance.